Viagra (sildenafil citrate) is the first of a new class of orally effective treatments for erectile dysfunction. It potently inhibits cGMP-specific phosphodiesterase type 5 (PDE5) (Fig 1),

found in high concentrations in the smooth-muscle cells of corpus cavernosum and in lesser concentrations in blood vessels of the systemic circulation. Because of its ability to act as [...]

To date, sildenafil citrate (Viagra) gives every evidence of being a safe drug for the eye despite a series of expressed concerns. A review of how its ocular safety profile has been identified offers insights into the strengths and weaknesses of present systems and resources for judging the ocular safety of Viagra or, for that [...]