Tag: responsiveness (Page 2)

Reliability, Validity, and Responsiveness of a 2-Min Walk Test To Assess Exercise Capacity of COPD Patients

Patients with COPD experience a wide variation in their levels of disability. Rehabilitation is recommended for COPD patients with moderate-to-severe disease who are aiming at reducing symptoms, improving quality of life, and increasing physical and emotional participation in everyday activities. Baseline and outcome assessments should be made in order to (1) quantify the patient’s functional […]

Normal Range of Methacholine Responsiveness in Relation to Prechallenge Pulmonary Function: Comment

The failure of FEVj-specific normal ranges of PD20FEVJ to improve sensitivity or specificity in detecting questionnaire-reported asthma or wheezing has several possible explanations. Measurements of airway responsiveness are imperfect at discriminating between asthmatics and nonasthmatics in population samples,’ and altering the criteria for an abnormal challenge test may have little impact relative to other sources […]

Normal Range of Methacholine Responsiveness in Relation to Prechallenge Pulmonary Function: Conclusion

A number of mechanisms have been proposed as the basis for the relationship between nonspecific airway responsiveness and prechallenge pulmonary function.’ Because resistance to flow through a tube is inversely proportional to the radius to the fourth power, a given degree of bronchoconstrictor-induced circumferential airway narrowing can be expected to cause a proportionally larger increase […]

Normal Range of Methacholine Responsiveness in Relation to Prechallenge Pulmonary Function: Analysis

Methacholine inhalation challenge testing was performed as previously described. Solutions were aerosolized by a nebulizer (DeVilbiss 646) powered by an air compressor (DeVilbiss). All inhalations were 6-s vital capacity inhalations followed by 2 s of breathholding. Seconds were counted aloud from a digital stopwatch after careful instruction and practice. Inhalations were done seated and wearing […]