Tag: nonacid reflux disease (Page 3)

Chronic Cough Due to Gastroesophageal Reflux Disease: Methods

The standard, catheter-based 24-h esophageal pH-monitoring study has its own inherent limitations. For example, because it cannot detect reflux events with a pH similar to that of the normal esophagus, the monitoring study can be entirely normal at a time when nonacid GERD is the cause of cough. In this situation, barium esophagography may be […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Research

Last, 24-h esophageal pH monitoring, lung scintiscanning after intragastric 99mTc-sulfur colloid infusion, investigating for lipid-laden alveolar macrophages in induced sputum or BAL fluid and observing the gross appearance of airway mucosal surfaces during laryngoscopy and bronchoscopy, and lung biopsy have been utilized to link GER with a variety of pulmonary diseases as well as cough. […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Laboratory Testing

A number of potential risk factors for GERD have been identified. These include the following: drugs such as alendronate, oral corticosteroids, bronchodilators such as inhaled (32-adrenergic agonists and theophylline in some studies, progesterone, calcium channel-blocking agents,anticholinergic agents, morphine, and meperidine; obesity; smoking; vigorous exercise,; alcohol; caffeine in some studies; fatty foods, chocolate, carminatives, and irritating […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Study

Aspiration syndromes associated with cough due to GERD include Mendelson syndrome, bacterial pneumonia and lung abscess, chemical pneumonitis, exogenous lipoid pneumonia, recurrent bacterial pneumonias, chronic interstitial fibrosis, bronchiectasis, Mycobacterium fortuitum or Mycobacterium chelonei pneumonia, diffuse aspiration bronchiolitis, and tracheobronchitis. While the character and timing of cough are not predictive of when GERD is likely to […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Recommendation

Because the term acid reflux disease when applied to chronic cough due to GERD can be a misnomer and may mislead clinicians into thinking that all patients with cough due to GERD should improve with acid-suppression therapy, it is recommended that the term acid reflux disease no longer be used in the context of cough […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Laryngoscopy

When GERD causes cough by irritating the larynx, laryngoscopy has the potential to demonstrate signs consistent with “reflux laryngitis” (eg, posterior laryngitis with red arytenoids and piled-up interarytenoid mucosa). Bronchoscopy and chest-imaging studies have the potential to detect abnormalities consistent with aspiration. Bronchoscopy may reveal airway signs consistent with aspiration (eg, subglottic stenosis,2 hemorrhagic tracheobronchitis, […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Pathophysiology

Physicians who manage patients with cough should be aware of these differences. While there is much that has been learned about a variety of esophageal and extraesophageal manifestations of GERD, this section will focus solely on chronic cough. Literature on screening for and managing complications of esophageal GERD, such as Barrett epithelium and esophageal cancer, […]