Jet nebulizers have typically been used to dispense water-soluble drugs from water or saline solution media. Many of the physical factors that control these aerosols have been studied, including the effect of air flow and pressure, changes in hygroscopicity resulting from dissolved salt or drugs, as well as design characteristics of the nebulizers. The ultimate […]
A computer model originally developed by Persons et al was modified according to MMAD and GSD and used to calculate regional deposition of the 18 aerosols. The human lung model was based on the following parameters: mouth breathing, functional residual volume 3,300 ml, tidal volume 750 ml, inspiration 2 s, expiration 2 s, no pause. […]
The Вес-DLPC liposomes in water (initial Bee concentration 0.5 mg/ml) were added to the jet nebulizer reservoir according to the maximum volume (Table 1). The nebulizers were selected at random and operated using dry compressed air at flow rates prescribed by the manufacturer’s instructions or at 7.5 to 8 L/min (Table 1). buy claritin online […]
Localized aerosol delivery of drugs to the respiratory tract is becoming an increasingly important and effective therapeutic method for treating a variety of pulmonary disorders. In this regard, several different devices have been used, including continuous-flow, jet nebulizers. To date, jet nebulizers have been used predominantly to administer aqueous preparations of soluble drugs such as […]