Tag: esophageal-bronchial cough reflex

Chronic Cough Due to Gastroesophageal Reflux Disease: Grade of Recommendation

In some patients, cough due to GERD will favorably respond to acid suppression therapy alone; proton pump inhibition may be effective when H2-antagonism has been ineffective; prokinetic therapy and diet, when added to proton pump inhibition, may be effective when proton pump inhibition alone has been ineffective. Level of evidence, low; benefit, substantial; grade of […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Grade of Recommendation

In patients with cough due to GERD, normal esophagoscopy findings do not rule out GERD as the cause of cough. Level of evidence, low; benefit, substantial; grade of recommendation, B For patients fitting the clinical profile for cough due to GERD, it is recommended that treatment be initially started in lieu of testing. Level of […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Recommendations

In patients with chronic cough, it should not be assumed that GERD has been definitively ruled out as a cause of cough simply because there is a history of antireflux surgery. Level of evidence, low; benefit, substantial; grade of recommendation, B In patients with chronic cough, while tests that link GERD with cough suggest a […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Summary of Recommendations

In patients with chronic cough due to GERD that has failed to improve with the most maximal medical therapy, which includes an intensive antireflux diet and lifestyle modification, maximum acid suppression, and prokinetic therapy, and the rest of the spectrum of treatment options in Table 3, cough may only improve or be eliminated with antireflux […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Prokinetic Therapy

In patients who meet the clinical profile predicting that silent GERD is the likely cause of chronic cough or in patients with chronic cough who also have prominent upper GI symptoms consistent with GERD, an empiric trial of medical antireflux therapy is recommended. Level of evidence, low; benefit, substantial; grade of recommendation, B For treating […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Drugs

Because coughing can induce GER events, it should be appreciated that less than optimal results may occur due to a cough-GER self-perpetuating cycle unless all causes of cough are adequately treated. Reliance on acid suppression alone may not only fail to adequately control the cough but also potentially place the patient at increased risk of […]

Chronic Cough Due to Gastroesophageal Reflux Disease: Patients

While the optimal way to treat all patients with cough due to GERD has yet to be determined, medical therapy in adults, based on the results of prospective and retrospective before-and-after intervention trials, when not limited to acid suppression therapy alone, has improved cough in 70 to 100% of patients. When cough in adults has […]