Tag: angii infusion

Vasoconstrictor Effects of Angiotensin II on the Pulmonary Vascular Bed: Discussion

The results of the present study showed that ANGII produced dose-related pressor effects on both the pulmonary and systemic vascular bed. However, the pulmonary vasculature was proportionately more sensitive to the vasoconstrictor effect of ANGII in comparison with the systemic vasculature. The increase in MPAP in response to the 4 ng/ kg/min dose of ANGII […]

Vasoconstrictor Effects of Angiotensin II on the Pulmonary Vascular Bed: Results

There were dose-related increases in concentrations of plasma ANGII (pmol/L), with significant differences between baseline and the three dose levels: baseline 32.9 (16.6 to 49.1); 2 ng/kg/min, 71.0 (54.8 to 87.3); 4 ng/kg/min, 112.3 (96.1 to 128.5); and 6 ng/kg/min, 148.4 (132.2 to 164.7). Numerical data for all other responses are shown in Table 1 […]

Vasoconstrictor Effects of Angiotensin II on the Pulmonary Vascular Bed: Methods

Activation of the renin-angiotensin system occurs in patients with hypoxemic cor pulmonale, with raised circulating levels of angiotensin II (ANGII) and aldosterone (ALDO).” The elevated levels of ALDO are responsible for producing renal-medi-ated sodium and water retention that manifests as edema in patients with cor pulmonale. The systemic pressor effects of ANGII are well documented, […]