Category: Pulmonary Function (Page 3)

Pleural Effusions in a Series of 181 Outpatients With Sarcoidosis: Conclusion

It is conceivable that pleural fluid formation is more frequent with active pulmonary sarcoidosis. A sarcoidosis-related PE was seen in 11.1% of our patients (1 of 9 patients) who had an exacerbation of pulmonary sarcoidosis compared to 0.6% of those who did not have an exacerbation (1 of172 patients). Although the frequency of sarcoid-related PEs […]

Pleural Effusions in a Series of 181 Outpatients With Sarcoidosis: Discussion

The diagnostic accuracy of the pleural fluid/serum protein ratio, the pleural fluid/serum LDH ratio, and the pleural fluid LDH concentration compared to the upper limits of normal for serum LDH concentration (using the criteria of Light et al) was prospectively examined by Joseph and colleagues by receiver operating characteristic analysis in a series of 200 […]

Pleural Effusions in a Series of 181 Outpatients With Sarcoidosis: Recommendation

Sarcoidosis-related PEs occur slightly more commonly in the right lung (45%) than in the left lung (33%). The reason for the right-sided predominance is unclear and is not related to organ involvement. Bilateral effusions have been reported in 22% of cases. Both of the sarcoid-related PEs in our series were bilateral, and organ involvement was […]

Pleural Effusions in a Series of 181 Outpatients With Sarcoidosis: Research

Sarcoidosis is a multisystem disease that is characterized by the presence of noncaseating granulomas. Sarcoidosis frequently involves the lung, lymph nodes, skin, eyes, and liver. When sarcoidosis involves the pleura, it may manifest as a PE, pneumothorax, pleural thickening, hydropneumothorax, trapped lung, hemothorax, or chylothorax. Since the first report by Schaumann on pleural sarcoidosis in […]

Pleural Effusions in a Series of 181 Outpatients With Sarcoidosis: Case

Small, bilateral PEs developed in a 57-year-old woman with newly-diagnosed stage 1 sarcoidosis. The pleural/serum protein ratio was in the exudative range with the pleural fluid lactate dehydrogenase (LDH)/upper limits of normal serum ratio borderline for an exudate. The cellular differential showed lymphocyte predominance. Acid-fast bacilli testing, fungal culture, and cytology findings were negative. Noncaseating […]

Pleural Effusions in a Series of 181 Outpatients With Sarcoidosis: Results

The presence of PE was determined using the following dynamic criteria, which were specific for fluid in the appropriate anatomic location, an anechoic or echogenic area showing: (1) change in shape due to respiratory movement, (2) the presence of a swirling or undulating motion in the suspected fluid collection, or (3) lung flapping. The determination […]