Category: Pulmonary Function (Page 14)

Relationship Between Expired Capnogram and Respiratory System Resistance in Critically III Patients During Total Ventilatory Support – Discussion

Precise knowledge of Rrs in patients receiving mechanical ventilation is needed for adequate clinical management. In intubated patients with normal lungs, the value of Rrs is usually less dian 4 cm H20/L/s, excluding the flow-resistive properties of the endotracheal tube and equipment. The contribution of these later components to the Rrs could be as high […]

Relationship Between Expired Capnogram and Respiratory System Resistance in Critically III Patients During Total Ventilatory Support – Data Analysis

Samples of blood were drawn in heparin-rinsed plastic syringes and were immediately analyzed for oxygen and carbon dioxide tensions (ABL 500, Radiometer Copenhagen, Copenhagen, Denmark). An on-line infrared C02 analyzer (HP78556A, Palo Alto, Calif) was used to continuously monitor C02 partial pressure changes and was placed between the distal port of the disposable humidifier and […]

Relationship Between Expired Capnogram and Respiratory System Resistance in Critically III Patients During Total Ventilatory Support – Methods

Modern ventilator monitoring includes the measurement of airway pressures and derived intermittent calculations such as respiratory system resistance (Rrs). Patients in the ICU receiving mechanical ventilation often exhibit high Rrs due to bronchospasm, structural airway abnormalities, low lung volume, and retained bronchial secretions both attached to the airways or to the wall of the endotracheal […]

N-Acetylcysteine Enhances Recovery From Acute Lung Injury in Man – Discussion

Despite major improvements in patient care, ARDS still remains a formidable clinical challenge and carries a high mortality rate. Recent clinical studies suggest that patients with ARDS undergo relevant oxidative stress. Toxic oxygen products cause cellular and subcellular damage and activate epithelial cells, macrophages, or endothelial cells. Oxygen radicals are also recognized as mediators between […]

N-Acetylcysteine Enhances Recovery From Acute Lung Injury in Man – Results

Statistical Methods Initial homogeneity assessment of the two groups was performed by t test and x2 analysis. The before and after comparisons were done with the sign test, the paired t test, and the Wilcoxon-Pratt test depending on the distribution of the data. Between-group comparisons were performed with the X2 test, the Student t test, […]

N-Acetylcysteine Enhances Recovery From Acute Lung Injury in Man – Methods

Multiple trauma included patients with multiple major fractures (two or more major long bones or unstable pelvic fracture) associated with trauma to another region of the body such as craniocerebral or abdominal, requiring surgical intervention. Aspiration was defined as recent (during the previous 6 h) inhalation of gastric contents, documented by suctioning of gastric material […]