Category: Asthma (Page 5)

Ciclesonide Reduces the Need for Oral Steroid Use in Adult Patients With Severe, Persistent Asthma

Inhaled corticosteroids (ICS) are the most effective agents for controlling persistent asthma. However, in very severe cases and during exacerbations, oral corticosteroids (OCS) are necessary. As systemic adverse events (AEs) are associated with OCS use, oral steroid-sparing strategies are employed and have been demonstrated with ICS such as be-clomethasone dipropionate, budesonide, and fluticasone propionate in […]

Chronic Cough Due to Asthma: Treatment

Despite the demonstrated efficacy of therapy with LTRAs in patients with CVA, the question of whether these agents are sufficient as monotherapy, or whether they should be used in addition to inhaled steroids, remains unresolved at this time, Subepithelial layer thickening, a pathologic feature of airway wall remodeling, is present in CVA, although to a […]

Chronic Cough Due to Asthma: Recommendation

Patients with cough due to asthma should initially be treated with a standard antiasthmatic regimen of inhaled bronchodilators and inhaled corticosteroids. Quality of evidence, fair; net benefit, substantial; grade of recommendation. A potential pitfall of inhaled steroid therapy in patients with CVA is that the treatment itself may induce or exacerbate cough, which is likely […]

Chronic Cough Due to Asthma: Evaluation

If reversible airflow obstruction is demonstrated in a patient with chronic cough, empiric therapy for asthma is appropriate, However, a patient with chronic cough due to asthma may present a diagnostic challenge, because physical examination and pulmonary function test results can be entirely normal, In this setting, bronchoprovocation testing with inhaled methacholine should be used […]