Monthly Archives: October 2014

Ciclesonide Reduces the Need for Oral Steroid Use in Adult Patients With Severe, Persistent Asthma: Safety

The investigators assessed patients for AEs; in addition, patients reported AEs in their patient diaries. Data from physical examinations and clinical laboratory tests were collected at screening and week 12. HPA-axis function was assessed at randomization and at week 12 via cosyntropin stimulation. Blood samples for serum cortisol measurements were collected before and after stimulation […]

Ciclesonide Reduces the Need for Oral Steroid Use in Adult Patients With Severe, Persistent Asthma

Inhaled corticosteroids (ICS) are the most effective agents for controlling persistent asthma. However, in very severe cases and during exacerbations, oral corticosteroids (OCS) are necessary. As systemic adverse events (AEs) are associated with OCS use, oral steroid-sparing strategies are employed and have been demonstrated with ICS such as be-clomethasone dipropionate, budesonide, and fluticasone propionate in […]